RNASET2 and neoplasm: RNASET2 is an enzyme that cleaves RNA, resulting in the degradation of transcripts and the production of nucleotide fragments with adenosine/guanosine terminus for G residues and a uridine residue for U residues.[17, 18] Although previous literature has shown a strong link between RNASET2 and tumor progression,[23, 25, 26, 27] its role in the progression of HCC has remained unclear.