UDPGA is a crucial substrate for glucuronidation carried out by UGTs and has previously been confirmed to sustain UGT activity.[43] To investigate whether UDPGA influences the expression of UGT1A1, exogenous UDPGA was introduced to RNASET2KO HCC cells, resulting in an increase in UGT1A1 levels (Figure S6F, Supporting Information). This evidence concerns the gene UGT1A1 and hepatocellular carcinoma.