SLC35A2 and hepatocellular carcinoma: UDPGA is a crucial substrate for glucuronidation carried out by UGTs and has previously been confirmed to sustain UGT activity.[43] To investigate whether UDPGA influences the expression of UGT1A1, exogenous UDPGA was introduced to RNASET2KO HCC cells, resulting in an increase in UGT1A1 levels (Figure S6F, Supporting Information).