A study worth mentioning for discussion include a group of 330 patients with similar characteristics (T2D, followed at a tertiary clinic) studied by Gautier et al31 These patients underwent an alternative approach to investigation through biopsy if they had consistently elevated levels of ALT—above 30 IU/L for men and above 20 IU/L for women. The gene discussed is GPT; the disease is type 2 diabetes mellitus.