We tested this hypothesis by comparing plasma cytokines, including IL-2, IL-5, IL-10, IL-13, IL-17A, IL-22, IL-33, IFN-γ, and TNF-α and the adipokine, leptin in normal weight and overweight/obese children, both with and without asthma in a cross-sectional study. This evidence concerns the gene TNF and asthma.