SERINC2 and alcohol dependence: In this study with an expanded sample size of a total of 1,167,439 participants of European, African or Asian descent with 18 diverse neuropsychiatric disorders, and harmonized genetic marker sets, analytical methods, meta-analysis and FDR correction, we confirmed that alcoholism was still the most significant disease associated with SERINC2 variants in European descent among all neuropsychiatric disorders.