No statistical differences in general patient information, including age, sex, body mass index (BMI), hypertension, diabetes mellitus, COPD, cigarettes, and advanced age (≥80), and inflammatory biomarkers [procalcitonin (PCT),C-reactive protein (CRP) and interleukin 6 (IL-6)] of the 1st day between the two groups (Table 1). The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.