A prospective, observational cohort study (Women’s cancer risk IDentification – quantitative polymerase chain reaction test for Endometrial Cancer, WID-qEC test) (60) based on the methylation of ZSCAN12/GYPC verified the presence of EC in 137 cervical smear specimens, with a sensitivity of 97.2% and a specificity of 75.8%. Here, ZSCAN12 is linked to cancer.