Cluster 2 (N=75) was characterized by oldest age (median age:78 years), highest elevation of inflammatory markers (median serum CRP levels:9.5 mg/mL), frequent complications of ILD (61.3%), and kidney involvements accompanied with an elevation of serum creatinine levels (88.0%, 1.26 mg/dl), as well as the highest ENT and neuron symptoms (30.7%, 65.3%, respectively). Here, CRP is linked to interstitial lung disease.