TPO and spindle cell hemangioma: Serum hsCRP levels were markedly elevated in SCH+ participants (4.2 ± 1.6 mg/L) compared to SCH- (3.1 ± 1.2 mg/L) and controls (2.0 ± 0.9 mg/L), indicating an inflammatory trend associated with anti-TPO positivity (P < 0.001).