DVT: deep vein thrombosis, SSNS: steroid-sensitive nephrotic syndrome, SDNS: steroid-dependent nephrotic syndrome, FRNS: frequently relapsing nephrotic syndrome, IFRNS: infrequently relapsing nephrotic syndrome, SRNS: steroid-resistant nephrotic syndrome, CRP: C-reactive protein, eGFR: estimated glomerular filtration rate, AKI: acute kidney injury. The gene discussed is CRP; the disease is steroid-resistant nephrotic syndrome.