The generated ROC curves based on the RT-qPCR data showed AUC > 0.9 for MAP3K1, MAP3K4, MAP3K7, MAP3K8, MAP3K9, and MAP3K10 genes in GC patients (Fig. 4A), which mean that these genes have the strong diagnostic abilities to distinguish GC patients from normal individuals. This evidence concerns the gene MAP3K4 and gastric cancer.