The BAF complex is primarily composed of ARID1A, ARID1B, SMARCA4, SMARCB1, SMARCE1, and SMARCC2, and heterozygous variant in either of them can lead to several distinct neurodevelopmental disorders (NDDs) with overlapping phenotypes, termed BAFopathies. The gene discussed is SMARCC2; the disease is neurodevelopmental disorder.