More specifically, BTF3 down-regulation (Fig. 3F) has been connected with the inhibition of transcription and protein synthesis in apoptotic K562 cells and is involved in the regulation of apoptosis in animal models (Jamil et al. 2015), suggesting that BFT3 downregulation could compromise cell viability in specific target organs to both T1DM and MS. Here, BTF3 is linked to myeloid sarcoma.