ARHGEF6 and nervous system disorder: In T1DM, some of the terms annotated were related to myelin dysregulation (ARHGEF6, CNP, NADK2, PSAP, SLC25A12) and other neurological disorders, such as Alzheimer’s disease (i.e., POA2, APOC1, APOC3, CNP, GSK3B, PON1, PSAP, SELENBP1) or movement disorders (Table 2).