In T1DM, some of the terms annotated were related to myelin dysregulation (ARHGEF6, CNP, NADK2, PSAP, SLC25A12) and other neurological disorders, such as Alzheimer’s disease (i.e., POA2, APOC1, APOC3, CNP, GSK3B, PON1, PSAP, SELENBP1) or movement disorders (Table 2). The gene discussed is APOC3; the disease is early-onset autosomal dominant Alzheimer disease.