EGFR and neoplasm: In evaluating the expression of FAM210B across different stages of LUAD, specifically the terminal respiratory unit (TRU), proximal-inflammatory (PI), and proximal-proliferative (PP) subtypes, as referenced in Collisson et al.‘s study [25], the results shown in Fig. S1B indicated that tumor samples in the TRU stage (which harbored the majority of EGFR-mutated tumors) exhibited a slight increase in expression compared to the PP and PI stages.