reported that TEVs carrying the mutant p53 protein can inhibit the glucose metabolism of CD4+ T cells by downregulating some rate‐limiting enzymes (such as the platelet isoform of phosphofructokinase, hexokinase‐I and phosphorylated‐pyruvate kinase M2) of glycolysis, subsequently functionally suppressing CD4+ T cells and leading to tumor immune escape.[239]. This evidence concerns the gene CD4 and neoplasm.