Besides inducing M2 polarization, impairing the anti‐tumor function of M1 macrophages can also lead to immune escape.[80]  Furthermore, macrophages have also been suggested to act as a relay station to display inhibitory molecules carried by TEVs, thereby mediating suppression of tumor immunity (Figure 2).  Golgi membrane protein 1 (GOLM1) is an oncoprotein highly expressed in multiple cancer types to promote cell proliferation, migration, and invasion, and inhibit apoptosis. The gene discussed is GOLM1; the disease is cancer.