MYC dysregulation is frequently observed in human cancers, including LUAD.[33] thereby initiating or sustaining tumor growth.[34] MYC dysregulation or MYC amplification is commonly observed in LUAD and can occur at any stage of tumor development.[35, 36] We analyzed the whole‐exome sequencing data from TCGA‐LUAD dataset and found increased copy number amplification of the MYC gene locus (8q24.21) in patients with MP‐subtype (Figure S1K, Supporting Information). This evidence concerns the gene MYC and cancer.