MYC and neoplasm: MYC dysregulation is frequently observed in human cancers, including LUAD.[33] thereby initiating or sustaining tumor growth.[34] MYC dysregulation or MYC amplification is commonly observed in LUAD and can occur at any stage of tumor development.[35, 36] We analyzed the whole‐exome sequencing data from TCGA‐LUAD dataset and found increased copy number amplification of the MYC gene locus (8q24.21) in patients with MP‐subtype (Figure S1K, Supporting Information).