Peripheral adiposity confers cardiovascular protection due to the secretion of adiponectin, which has an anti-inflammatory effect [36], in contrast to VAT, which secretes interleukin-6, interleukin-8, angiotensinogen, vascular endothelial growth factor, monocyte chemoattractant protein-1, promoting more chronic inflammation and dyslipidemia [14]. The gene discussed is ADIPOQ; the disease is metabolic syndrome.