Compared to “normal” children, children classified as “low leptin/IGF-1/HbA1c” were less likely to have a family history of diabetes (0.26 [0.08;0.86]; odds ratio (OR) and 95% confidence interval) or hypertension (0.53 [0.29;0.99]) and the children (0.32 [0.27;0.38]) as well as their mothers (0.93 [0.88;0.98]) had a lower BMI. The gene discussed is IGF1; the disease is Hypertension.