Additionally, it has been shown that administration of 17β‐oestradiol differentially modulated oxidative stress depending on sex, infection, and tissue in P. berghei ANKA‐infected mice: In the blood, 17β‐oestradiol did not alter superoxide dismutase (SOD) activity but increased catalase (CAT) activity only in intact females, and gonadectomy reduced glutathione peroxidase (GPx) activity in both sexes with 17β‐oestradiol reconstitution only boosting it in females. The gene discussed is CAT; the disease is infection.