BCL2 and breast carcinoma: In the Bcap37 breast cancer cell model, the buckwheat protein bioactive peptide extracts significantly altered the morphology of breast cancer cells, causing severe cell cycle arrest in the G0/G1 phase, and significantly downregulating Bcl-2 protein content while upregulating Fas protein content, thus exerting anti-breast cancer effects (Guo et al., 2010).