We observed that an elevated expression of RAC1 is associated with a Gain status in CNV, surpassing the expression observed in instances where CNV status was either Neutral or characterized by a Loss in 20 tumour types, including GBM, GBMLGG, LGG, CESC, LUAD, COAD, READ, BRCA, ESCA, STES, SARC, STAD, UCEC, HNSC, LUSC, LIHC, MESO, OV, TGCT, SKCM and BLCA (Fig. S3a). Here, RAC1 is linked to glioblastoma.