Here, high expression levels in SMPD1, and low expression in GLTP, B3GALT4, and ST8SIA6 were significantly correlated with worse prognosis, suggesting a significant relations to SMPD1, GLTP, B3GALT4, and ST8SIA6 expression level of the development and prognoses of the CRC patients (Figure 5C). Here, SMPD1 is linked to colorectal carcinoma.