RIP-qPCR results indicated that ATG3 mRNA was significantly immunoprecipitated from HCC cells transfected with YTHDF1-WT, while the interaction between YTHDF1-MUT and ATG3 mRNA was significantly decreased, implying the pivotal role of m6A-binding pocket of YTHDF1 in its interaction with ATG3 mRNA (Figure 7G). Here, YTHDF1 is linked to hepatocellular carcinoma.