TPO and Schnyder corneal dystrophy: SCD: sickle cell disease; PJI: prosthetic joint infection; AVN: avascular necrosis; HB: hemoglobin; VOEs: vaso-occlusive pain events; TPO: thyroid peroxidase; ONFH: osteonecrosis of the femoral head; ATMP: advanced therapeutic products; THR: total hip replacement; HHS: Harris Hip Score