Pearson's R analysis results were represented in volcano plots (Fig. S3A–H), which includes analyses for IRF1 in breast invasive carcinoma, esophageal carcinoma (ESCA), and lung adenocarcinoma (LUAD), IRF2 in breast invasive carcinoma and esophageal carcinoma, IRF3 in breast invasive carcinoma and kidney renal clear cell carcinoma, and IRF5 in brain lower grade glioma. Here, IRF1 is linked to carcinoma of esophagus.