Our previous studies also demonstrated that EphA2 is obviously upregulated in NPC cell lines and tissues, and promotes NPC cell growth, invasion, metastasis and stem properties, and EphA2 expression levels were negatively correlated with NPC patient survival 11-13, suggesting that EphA2 can serve as a therapeutic target in NPC. Here, EPHA2 is linked to nasopharyngeal carcinoma.