DLL3 and neoplasm: AMG119 is a DLL3-CAR T-cell product consisting of a DLL3 antigen-binding domain-targeting, CD28, 4-1BB co-stimulatory binding domain-conjugated CD3 domain autologous inactivating lentiviral vector, which has shown long term anti-tumor activity in preclinical studies in DLL3-expressing SCLC cells.