BCL2L12 and central nervous system cancer: To investigate the effects of the phosphorylation status of T33 in BCL2L12 on glioma development, we stably overexpressed various versions of BCL2L12 in U251MG cells, including wild-type (WT), phospho-mimic (T33E), and phospho-dead (T33A) mutant, and xenografted them into the immunocompromised mice.