To investigate the association between CKS1B expression and chemotherapy resistance in PDAC, as well as to elucidate the underlying mechanisms, we downloaded the expression data of TCGA-PAAD from UCSC XENA based on the GDSC drug database, and then used as a test data for the “calcPhenotype” function of the “oncoPredict” package. The gene discussed is CKS1B; the disease is pancreatic adenocarcinoma.