ADAR and neoplasm: For example, Kyle A and his team proposed in 2021 that ADAR1 is highly expressed in TNBC and that knockdown of ADAR1 attenuates the proliferation of tumor cells115; a report by Kyle A and his team in April 2024 showed that targeting ADAR1 and DHX9 could exert anti-tumor effects by inducing viral mimicry, suggesting that both could serve as effective tools for breast and other cancers116.