Four studies reported values for three different types of prostaglandin E synthase (PGES) levels in post-mortem brains: microsomal prostaglandin E synthase-1 (mPGES-1) (Mohri et al., 2007; Chaudhry et al., 2008; Akitake et al., 2013), microsomal prostaglandin E synthase-2 (mPGES-2) (Mohri et al., 2007; Akitake et al., 2013; Chaudhry et al., 2010) and cytosolic prostaglandin E2 synthase (cPGES) (Mohri et al., 2007; Chaudhry et al., 2008, 2010; Akitake et al., 2013) in post-mortem brains of patients with AD (Supplementary Table 7). Here, PTGES2 is linked to Alzheimer disease.