Increase in CXCR3 CD226 CD4 in sarcoidosis • CXCL9 and CXCL11 are ligands of CXCR3, are IFN-inducible and found in granulomas.• CXCR3 expressing CD4+ T cells are recruited in granuloma.B cells: more prevalent in the BAL of sarcoidosis and CTD-ILD patients compared to IPF. The gene discussed is CD226; the disease is Granuloma.