ROC curves were plotted for CTSB, IL10, and AGER, demonstrating that CTSB (AUC=0.98), IL10 (AUC=0.83), and AGER (AUC=0.87) effectively distinguished IPF from controls, indicating their potential diagnostic markers for IPF (Figures 5A–C). This evidence concerns the gene AGER and idiopathic pulmonary fibrosis.