We obtained methylation maps of SLC3A2, NUBPL, ACTB, and DSTN from the MethSurv database, presented in a heatmap (Supplementary Figure 11C), identifying 60 CpG sites with multiple CpG sites of DRGs showing low methylation in HNSCC patient samples. The gene discussed is NUBPL; the disease is head and neck squamous cell carcinoma.