A biopsy revealed anaplastic lymphoma kinase (ALK) -negative ALCL (CD3-, CD4+, CD5-, CD8-, CD30+, CD56-, ALK-, TIA-1-, Granzyme B-, Perforin-, Epstein-Barr virus-encoded small ribonucleic acid (EBER)- (Fig. 1). The gene discussed is ALK; the disease is anaplastic large cell lymphoma.