The genes in these corresponding clusters have been associated with the suppression of adaptive immune responses.32-35 The M2 macrophage markers CSF1R, PTGES2, and FOLR2 were primarily expressed within the tumor core whereas MARCO, C1Q, and S100A9 were expressed in the extratumoral regions of the tissues (Supplemental Figure 1). The gene discussed is FOLR2; the disease is neoplasm.