At presentation, CDH23 and BEST1 exhibited the largest hyper-AF area in the under 18-year-olds, MY07A and BEST1 in the 18- to 30-year-olds, CRB1, RDH12, and BEST1 in the 30- to 45-year-olds, and NR2E3 and CDH23 in the over 45-year-olds (Fig S6, available at www.ophthalmologyscience.org). Here, CRB1 is linked to atrial fibrillation.