CHM and atrial fibrillation: As well as genotype–phenotype associations, we also found associations at the individual variant level confirming the known association between the p.(Gly1961Glu) variant in ABCA4 and the presence of a macular ring (Fig S7).44, 45, 46, 47 When considering feature prevalence from the fovea, we found, as expected, that genes usually associated with cone–rod degeneration showed a decrease in hypo-AF extent moving away from the fovea but with an opposite trend for the RP genes and CHM (Fig 9A).