In addition to these WT rat studies, it would also be worthwhile if we could see how Bet1L serves in maintaining NMJ integrity under peripheral nerve damage and neuromuscular disorders, such as spinal muscular atrophy and myasthenia gravis, which have been known to link to NMJ degeneration and distal axonopathy in pathology. This evidence concerns the gene BET1L and proximal spinal muscular atrophy.