Bet1L siRNA-injected ALS rats had significantly lower levels of innervated NMJs (P < 0.05, 47.4 ± 7.3%) when compared to all three controls (76.0 ± 7.9% scrambled, 77.9 ± 4.3% vehicle, and 72.9 ± 5.8% no injection, n = 7 each group; Figure 4B). Here, BET1L is linked to amyotrophic lateral sclerosis.