In contrast, the cell diameter of motor neurons in Bet1L siRNA-injected ALS rats (73.3 ± 1.9 mm, n = 140, P < 0.05) was significantly lower than all controls: 91.6 ± 1.8 mm in scrambled siRNA (n = 91), 94.9 ± 2.6 mm in vehicle only (n = 85), and 81.4 ± 1.9 mm in no injection (n = 126) (Figure 5B right). This evidence concerns the gene BET1L and amyotrophic lateral sclerosis.