BDNF and hepatocellular carcinoma: Supplementary analyses of training time point as a categorical variable (T0–T3) confirmed that BDNF increase at each posttraining time point was mediated by HCC reduction (ACMEs, 0.043–0.090, 11.1%–32.2% mediation; all ps ≤ .25) (see Figure S3 and Table S9).