Research in HER2-positive gastric cancer cell lines has also indicated that DS-8201 has the capacity to modulate immune-related pathways, particularly the cGAS-STING pathway, enhance the gene expression signature of tumor immunogenicity, promote IFN-1 response, and induce DCs activation, which in turn leads to increased tumor cell cytotoxicity (30). The gene discussed is CGAS; the disease is neoplasm.