Several clinical features have been suggested to increase the likelihood of cCR, including low levels of carcinoembryonic antigen (CEA) (53–56), small tumor size (57, 58), low tumor/nodal stage (59), low histological grade (60), a small range of tumor circumference (61), high hemoglobin levels (53, 60), and a low neutrophil-to-lymphocyte ratio (61). Here, CEACAM5 is linked to neoplasm.