Excessive production of pro-inflammatory cytokines such as interleukin-1β (IL-1β), interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-17 A (IL-17 A) alongside other proinflammatory cytokines by neutrophils is known to play a pivotal role in the formation of NETs and the initiation of SIRS [26–29]. The gene discussed is IL17A; the disease is systemic inflammatory response syndrome.