The network pharmacology analysis revealed that the compounds in CHF, including luteolin (A1), kaempferol (A2), quercetin (A3), dan-shexinkum d (SM32), arachidonic acid (LJ5), isorhamnetin (LJ6), choline (TM3), and others were related to the targets associated with FLHS and OS, such as PPARG, PPARD, PPARA, APOB, NFE2L2, SOD1, HMOX1, NQO1, etc. It was found that compounds such as quercetin and kaempferol can enhance lipid metabolism and reduce the oxidative stress [28]. This evidence concerns the gene APOB and congestive heart failure.