G6PD and neoplasm: As demonstrated in Figure 4C, BANCR and G6PD were mainly coexpressed and colocalized in the cytoplasm of cell lines and ccRCC tumor cells, which not only confirmed the ectopic expression of G6PD in ccRCC but also suggested a potential interaction between BANCR and G6PD (6, 15, 16, 17, 18, 19).