Notably, enriched pathways (adjusted p < 0.05, Benjamini–Hochberg corrected) included the complement and coagulation cascades, cytokine-cytokine receptor interaction, transcriptional misregulation in cancer, chemokine signaling pathway, neutrophil extracellular trap formation, NOD-like receptor signaling pathway, fluid shear stress and atherosclerosis, osteoclast differentiation, TNF signaling pathway and toll-like receptor signaling pathway (Fig. 2B). This evidence concerns the gene TNF and cancer.