Consistent with these results, we also discovered that, compared with the Mir142+/+BCR-ABL mouse [a CP CML model17], T cells in the Mir142−/−BCR-ABL mouse [a BC CML model16] had higher rate of spontaneous apoptosis and were significantly decreased. The gene discussed is MIR142; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.