In contrast, the rates of ANA positivity significantly increased in the COVID-19 group, with 97 individuals (48.5%) testing positive for dsDNA, 81 (40.5%) for ENA, and 84 (42%) for Hep-2 nucleus antibodies (p < 0.05) (Figs. 2, 3, and 4). This evidence concerns the gene BTG3 and COVID-19.