Moreover, four T-DNA samples carried alterations in exon 3 of CTNNB1: a missense mutation of unknown clinical significance in one CPA-CS (p.Leu46Pro), a pathogenic/likely pathogenic missense mutation in one CPA-MACS (p.Ser45Pro), and an in-frame deletion (pThr42_Pro44del) followed by a pathogenic/likely pathogenic missense mutation (pSer45Phe) on the same allele in another CPA-MACS, and a pathogenic/likely pathogenic missense mutation (pSer45Phe) in one CPA-MACS. The gene discussed is CPA1; the disease is congenital primary aphakia.