TXN2 and metabolic dysfunction-associated steatotic liver disease: Therefore, estrogens, through their antioxidant properties [50], can modulate redox signaling pathways, hence shaping the overall antioxidant cellular response: TRX2 may play a role and exert compensative antioxidant function, and therefore, the role we have described in our in vitro study has to be related to the MASLD pathogenesis.