They demonstrated that differences in the PI3K/AKT pathway are responsible for the different responses of obese and nonobese cervical cancer patients to standard radiotherapy and chemotherapy.[61] Meanwhile, Jungles et al also stated that cervical cancer patients with greater BMI were more sensitive to standard chemoradiotherapy, which could be explained by fat cells releasing more monounsaturated and diunsaturated free fatty acids and activating beta oxidation.[62,63] But obviously, it needs additional confirmation in the future. This evidence concerns the gene AKT1 and cervical carcinoma.