The internal mechanisms have not been clarified, and some changes in immune-related indexes still need to be explored (e.g., IL-10 is elevated in Stevens Johnson Syndrome/Toxic Epithelial Neoplasia [SJS/TEN] but has not been confirmed in AGEP[3]), and most of them are thought to be T-cell-mediated delayed hypersensitivity reactions.[4] At present, it is mainly timely identification and symptomatic treatment, and the differential diagnosis and drug therapy are discussed below. Here, IL10 is linked to toxic epidermal necrolysis.